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Rated 4.9/5 from 5,281 Reviews
Cut Calories, Not Strength — The Only Liquid HMB Formula Designed For GLP-1 Users.
Why lose your muscle along with the weight when you can protect it with just 1 drop in your morning coffee?
Blocks muscle breakdown during extreme caloric restriction
Just 1 drop in your morning coffee
Zero calories, zero nausea, zero effort
In stock, ready to ship
*We recommend 3-6 months of consistent use for best results
Made In The USA
Third-Party Tested
60-Day Money
Back Guarantee
NSF Certified
Losing Weight and
Losing Yourself?
Muscle loss is the silent side effect of GLP-1 medications that no one talks about. But getting quality muscle protection can make a BIG difference.
If you're losing weight on Ozempic, Wegovy, or Mounjaro, you're not just dealing with fat loss—you're experiencing extreme caloric restriction that triggers muscle breakdown 24/7. Poor muscle protection can impact every aspect of your life—from your energy levels to your long-term metabolism.
The real issue? Most muscle-protection solutions don't fit your reality. Large pills you can't swallow. Thick protein shakes that worsen your nausea. The longer you wait, the more muscle you lose.
But Here's The Good News…
Now it's possible to protect your muscle during GLP-1 weight loss.
BioForm Muscle Defense is your easiest solution to preserve muscle and maintain a healthy metabolism.
It doesn't require lifestyle changes...
It doesn't worsen your nausea...
It's not hard to take...
It's just a natural, effective liquid formula that delivers 8 muscle-protecting benefits every morning.
What is HMB and Why Does the
Liquid Format Matter?
HMB (beta-hydroxy beta-methylbutyrate) is a naturally occurring compound clinically proven to block muscle breakdown during extreme caloric restriction—exactly what happens when you're on Ozempic, Wegovy, or Mounjaro and eating under 1,000 calories a day.
Here's the problem: For decades, HMB has only been available in large pills or thick powders designed for bodybuilders—not for people dealing with severe GLP-1 nausea who can barely stomach anything.
That's what makes BioForm different. This is the ONLY HMB formula in pure liquid form. No pills to gag on. No thick, chalky powder. Just 1 tasteless dropper in your morning coffee that you won't even notice—but your muscles will.
Why does format matter? Because compliance is everything. The best supplement in the world is useless if you can't tolerate it consistently. Liquid works when pills and powders fail.
BioForm® Muscle Defense
Clinical-dose liquid designed specifically for GLP-1 users. No pills to swallow. No thick shakes to choke down. Just 1 dropper in your coffee that protects your muscle while you lose weight. Third-party tested. FDA approved facility.
Protect your muscle while your GLP-1 melts fat
1 drop in coffee—5 seconds, done
Keep your face full, your strength up, your results lasting
$67 $46 Huge Black Friday Savings
Buy One
(30 Servings)
$46
/bottle
Save $90
Buy Three
(90 Servings)
$37
/bottle
Buy Two
(60 Servings)
$42
/bottle
Sampler
Best Value
Most Popular
FREE U.S. SHIPPING with every order!
This is a one time purchase - not a subscription.
*We recommend 3 months of consistent use for best results
BioForm Muscle Defense Is Unlike Any Other HMB Supplement
Natural, effective, and works with your body's own muscle-protection pathways. BioForm isn't just another supplement—it's a scientifically-formulated liquid designed specifically for GLP-1 users who need muscle protection but can't tolerate pills or powders.
Experience superior absorption: Our sublingual liquid formula delivers up to 95% bioavailability—nearly 2x more effective than pills or powders—so you get maximum muscle protection from every drop.
Preserve muscle, protect metabolism with BioForm's natural liquid HMB supplement.
92% of customers
report maintaining muscle mass
88% of customers
maintained strength levels
95% of customers
saw visible muscle definition within 6 weeks
100% Natural Ingredients
Fast-Acting Formula
Vegan-Friendly
Drug-Free Solution
Third-Party Tested
Made in the USA
60-Day Guarantee
BioForm Muscle Protection: Benefits That Compound Over Time
Day 1
IMMEDIATE PROTECTION
From your very first dropper, BioForm begins blocking muscle protein breakdown, protecting your lean tissue during caloric restriction.
Week 1
STRENGTH MAINTAINED
In just one week, you'll notice you're maintaining your strength during workouts and daily activities—no more feeling weak or depleted.
Week 2
VISIBLE DEFINITION
Two weeks in, friends and family notice you're looking stronger and healthier—not gaunt or drawn despite rapid weight loss.
Week 3
ENERGY RESTORED
By week three, experience improved metabolic function and energy levels as your body benefits from consistently protected muscle tissue.
Month 1
METABOLIC PROTECTION
After one month, notice improvements in your overall metabolism, body composition, and confidence that your results will last.
Month 2 & Beyond:
SUSTAINABLE RESULTS
Experience the cumulative benefits of protected muscle: maintained metabolism, stronger immune system, and long-term weight management success.
Your Path to Protected Muscle
Follow these simple steps to experience maximum muscle protection during your GLP-1 weight loss journey.
Real Results from Real GLP-1 Users
See how BioForm helped thousands protect their muscle, maintain their strength, and keep their results—without the gaunt, depleted look.
30 DAY
RISK FREE
TRIAL
Pharmaceutical-Grade Quality You Can Trust
Our clinical-grade liquid formula delivers the exact dose shown in peer-reviewed studies published in the Journal of Applied Physiology and Nutrition & Metabolism to block muscle protein breakdown during extreme caloric restriction.
We then carefully added Vitamin D3 to support bone health and immune function during rapid weight loss—two critical nutrients that GLP-1 users are often deficient in, now delivered in one effortless formula.
Every batch is third-party tested and NSF Certified for purity and potency. Made in an FDA-registered facility in the USA with pharmaceutical-grade ingredients. No proprietary blends hiding doses. No fillers. No artificial ingredients. No soy. Just pure, concentrated muscle protection.
Developed in partnership with physicians specializing in obesity medicine who were tired of seeing their patients lose muscle along with fat—and frustrated that existing HMB products (pills and powders) weren't tolerable for nauseous GLP-1 users who need them most.
That's why we created the first—and only—liquid HMB formula specifically designed for the GLP-1 experience. Not adapted from bodybuilding formulas. Built from the ground up for people dealing with severe appetite suppression and nausea.
Frequently Asked Questions
How do your Muscle Defense supplements work?
BioForm Muscle Defense delivers 3g of clinical-dose HMB in liquid form—the exact amount shown in peer-reviewed studies to block muscle protein breakdown during extreme caloric restriction. Unlike protein (which only provides building blocks), HMB actively signals your body to STOP breaking down existing muscle tissue for energy. The liquid format ensures maximum absorption and zero GI distress, making it the only HMB solution designed specifically for GLP-1 users dealing with nausea and appetite suppression.
How does the 60-day trial work?
Try BioForm Muscle Defense completely risk-free for 60 days. If you don't see visible muscle preservation, improved strength, or better body composition—or if you simply don't love it—we'll refund 100% of your purchase price. No questions asked. No return shipping required. Just email us and we'll process your refund immediately. We're that confident in our formula because we've seen it work for over 5,000 GLP-1 users.
How does the subscription work?
Our Subscribe & Save program delivers fresh BioForm automatically every 30, 60, or 90 days (your choice) at 10% off regular pricing. You get free priority shipping, can skip or delay any shipment, and cancel anytime—no commitment required. Plus, subscribers get exclusive early access to new products and formulations. Most customers choose the 90-day subscription (3 bottles every 3 months) for maximum savings and convenience.
Is it worth subscribing?
Absolutely. Here's why 87% of our customers subscribe: (1) You save 10% on every order, (2) You never run out—consistency is critical for muscle protection, (3) Free priority shipping always, (4) Cancel, skip, or delay anytime with one click, (5) Priority customer support. Most importantly, muscle protection requires daily use. Missing even a few days during extreme caloric restriction can result in significant muscle loss. Subscription ensures you're always protected.
Will this interact with my GLP-1 medication?
No. HMB (beta-hydroxy beta-methylbutyrate) is a naturally occurring metabolite of the amino acid leucine that your body already produces. BioForm simply provides a clinical dose that your body can't make on its own during extreme caloric restriction. It does not interact with semaglutide (Ozempic, Wegovy), tirzepatide (Mounjaro, Zepbound), or any other GLP-1 receptor agonist. However, we always recommend discussing any new supplement with your prescribing physician, especially if you're on multiple medications.
How is this different from protein powder?
Completely different mechanisms. Protein powder provides amino acid building blocks, but doesn't STOP muscle breakdown—it only supports muscle building (which is hard when you're eating 900 calories/day and exhausted). HMB actively blocks the breakdown pathway itself. Think of it this way: protein is the bricks to build a house, but HMB is the security system preventing someone from tearing it down. You need both, but HMB is specifically designed to preserve what you have during caloric restriction. Plus, our liquid format won't trigger nausea or require forcing down thick shakes.
When will I see results?
Most users notice they're maintaining strength during workouts within the first week. Visible muscle definition (especially facial fullness) becomes apparent within 2-3 weeks. For measurable body composition changes (DEXA scan, InBody, etc.), we recommend a full 60-day trial since muscle preservation is a gradual process. Remember: you're not trying to BUILD muscle right now—you're trying to KEEP the muscle you have while losing fat. That's a subtle but critical difference you'll see reflected in how you look, how you feel, and how your clothes fit.
Our 60-Day "Love It Or It's Free" Guarantee
We're so confident BioForm Muscle Defense will protect your muscle during GLP-1 weight loss that we offer an industry-leading 60-day money-back guarantee.
Try it risk-free for a full 60 days. If you don't see maintained strength, visible muscle definition, and improved body composition—or if you simply don't love it—we'll refund 100% of your purchase price.
No questions asked. No hoops to jump through. No return shipping required.
Just email support@getbioform.com and we'll process your refund immediately.
Why 60 days? Because real muscle protection takes time. We want you to experience the full benefits of clinical-dose HMB, track your progress with DEXA scans or measurements, and see the difference in how you look and feel.
If BioForm isn't the easiest, most effective muscle protection you've ever used—you pay nothing.
You Have Two Options.
Six months from now, you'll either be weaker and gaunt with a slower metabolism—or stronger, healthier, with your results protected.
One dropper in your coffee. Five seconds. That's the entire effort.
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60-day money-back guarantee
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